TGD introduces several new concepts, such as the new view of space-time and classical fields. TGD also predicts a new quantum ontology predicting phases of ordinary particles labelled by effective Planck constant heff behaving like dark matter and residing at the field bodies. Zero energy ontology (ZEO) is part of the new quantum ontology. The basic challenge has been the fusion of these notions with the standard approach involving electromagnetic fields and biochemistry. In particular, the Pollack effect and its generalizations have turned out to be central in the development of TGD based views of living matter. Also the TGD views of cell membrane and of neuron and nerve pulse and EEG examples should be integrated with standard biochemistry- and bio-electricity based approaches.
For me the challenge has been and still is the fact that biochemical thinking is very different from that of a theoretical physicist thinking in terms of action principles, field equations, and quantum theory. In order to understand the stunning complexities of biochemistry one must learn the key concepts at an intuitive level.
Of course, notions such as acids and bases and electrolysis, electronegativity, oxidation, reduction, and redox reactions belong to the basic conceptual arsenal. One should also understand how these notions relate to basic biological processes such as photosynthesis, chemical storage of metabolic energy and respiration. One begins to learn the significance of these notions as one tries to understand how to test whether some sample, taken for instance from Mars, contains organics possibly produced by the decay of living organisms.
Could the new physics provided by TGD provide totally new insights about biology and biochemistry? The mechanisms leading to emergence of the basic organic molecules serving as building bricks of basic information molecules like amino acids, DNA and RNA are poorly understood. The extreme efficiency of biocatalysis remains a mystery in the biochemistry based approach: more concretely, where does the energy making it possible to overcome potential barriers preventing the reactions come from? How did the basic information molecules and genetic code emerge and why is the genetic code what it is? Is there some hidden new physics behind the replication of DNA, its transcription of DNA to mRNA, and translation of mRNA to proteins? How did the genetic code evolve?
I am not a biochemist and the article linked below is also an attempt to clarify these notions for myself. Google AI allows anyone to get detailed accounts of the basic notions and has been of considerable help in fact checking and learning of new facts about basic biochemistry during the writing of the article. I will also discuss some examples related to the evidence for life on Mars and the recent finding of JWST that organic molecules relevant for life existed much before the planet Earth.
See the article A possible TGD based narrative for how life might have evolved.
For a summary of earlier postings see Latest progress in TGD.
For the lists of articles (most of them published in journals founded by Huping Hu) and books about TGD see this.
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